{"id":820,"date":"2013-09-23T21:05:58","date_gmt":"2013-09-23T21:05:58","guid":{"rendered":"http:\/\/oxygenworldwide.wordpress.com\/?p=820"},"modified":"2013-09-23T21:05:58","modified_gmt":"2013-09-23T21:05:58","slug":"miniature-oxygen-generator-implants-to-boost-effectiveness-of-cancer-treatments","status":"publish","type":"post","link":"https:\/\/www.oxygenworldwide.com\/en\/miniature-oxygen-generator-implants-to-boost-effectiveness-of-cancer-treatments\/","title":{"rendered":"Miniature oxygen generator implants to boost effectiveness of cancer treatments"},"content":{"rendered":"<p>\t\t\t\t<a href=\"https:\/\/www.oxygenworldwide.com\/wp-content\/uploads\/2013\/09\/oxygen-generator.jpg\"><img decoding=\"async\" class=\"aligncenter size-medium wp-image-821\" alt=\"oxygen-generator\" src=\"https:\/\/www.oxygenworldwide.com\/wp-content\/uploads\/2013\/09\/oxygen-generator.jpg?w=300\" width=\"300\" height=\"168\" srcset=\"https:\/\/www.oxygenworldwide.com\/wp-content\/uploads\/2013\/09\/oxygen-generator.jpg 530w, https:\/\/www.oxygenworldwide.com\/wp-content\/uploads\/2013\/09\/oxygen-generator-300x168.jpg 300w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><br \/>\nSome cancers, such as pancreatic and cervical cancers, are notoriously hypoxic, which means they contain low oxygen levels. Because radiation therapy needs oxygen to be effective, hypoxic areas of a tumor can be difficult to kill. To combat this, researchers at Purdue University have developed and tested a miniature electronic device that is designed to be implanted into solid tumors to generate oxygen and boost the effectiveness of radiation and chemotherapy treatments.<br \/>\nOnce implanted into a tumor, the new &#8220;implantable micro oxygen generator&#8221; uses ultrasonic signals to generate a small voltage to separate oxygen and hydrogen from water in a chemical process called water electrolysis. The devides are just under one centimeter (0.39-in) long and are inserted into tumors with a hypodermic biopsy needle.<\/p>\n<div><a href=\"http:\/\/www.gizmag.com\/miniature-oxygen-generator\/19703\/picture\/141390\/\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" alt=\"The design of the miniature oxygen generator (Birck Nanotechnology Center, Purdue Universi...\" src=\"http:\/\/images.gizmag.com\/inline\/oxygen-generator-0.jpg\" width=\"530\" \/><\/a><\/div>\n<p>&#8220;We are putting these devices inside tumors and then exposing the tumors to ultrasound,&#8221; said Babak Ziaie, a Purdue University professor of electrical and computer engineering and biomedical engineering. &#8220;The ultrasound energy powers the device, generating oxygen.<br \/>\nThe devices, which were created at the Birck Nanotechnology Center in Purdue&#8217;s Discovery Park, have been tested in pancreatic tumors implanted in mice. The tests showed the devices generated oxygen, which resulted in the tumors shrinking faster than tumors without the devices.<br \/>\nThe\u00a0<a href=\"http:\/\/www.purdue.edu\/\" target=\"_blank\" rel=\"noopener\">Purdue<\/a>\u00a0researchers have filed a patent for the current design and are looking at the possibility of redesigning it to make it more practical for manufacturing and clinical trials.<br \/>\nThe results of the team&#8217;s research appear in a paper published online in<em><a href=\"http:\/\/tbme.embs.org\/\" target=\"_blank\" rel=\"noopener\">Transactions on Biomedical Engineering<\/a><\/em>.<br \/>\n<img decoding=\"async\" alt=\"\" src=\"http:\/\/ap.lijit.com\/www\/delivery\/retarget.php?p=FMC&amp;add_s329=1&amp;add_n100=1\" width=\"0\" height=\"0\" border=\"0\" \/><img decoding=\"async\" alt=\"\" src=\"http:\/\/ib.adnxs.com\/seg?add=974292&amp;t=2\" width=\"0\" height=\"0\" border=\"0\" \/><br \/>\nAbout the Author<\/p>\n<div id=\"authorcontainer\"><a href=\"http:\/\/www.gizmag.com\/author\/darren-quick\/\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" id=\"bio_pic\" alt=\"Darren Quick\" src=\"http:\/\/images.gizmag.com\/author_profiles\/34.jpg\" \/><\/a>Darren&#8217;s love of technology started in primary school with a Nintendo Game &amp; Watch Donkey Kong (still functioning) and a Commodore VIC 20 computer (not still functioning). In high school he upgraded to a 286 PC, and he&#8217;s been following Moore&#8217;s law ever since. This love of technology continued through a number of university courses and crappy jobs until 2008, when his interests found a home at Gizmag. \u00a0\u00a0<a href=\"http:\/\/www.gizmag.com\/author\/darren-quick\/\" target=\"_blank\" rel=\"noopener\">All articles by Darren Quick<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Some cancers, such as pancreatic and cervical cancers, are notoriously hypoxic, which means they contain low oxygen levels. Because radiation [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":821,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"iawp_total_views":1,"footnotes":""},"categories":[6],"tags":[],"class_list":["post-820","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-portable-oxygen"],"_links":{"self":[{"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/posts\/820","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/comments?post=820"}],"version-history":[{"count":0,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/posts\/820\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/media\/821"}],"wp:attachment":[{"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/media?parent=820"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/categories?post=820"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oxygenworldwide.com\/en\/wp-json\/wp\/v2\/tags?post=820"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}